- Title
- Psychometric evaluation of an experience sampling method–based patient-reported outcome measure in functional dyspepsia
- Creator
- Klaassen, Tim; Smeets, Fabienne G. M.; Leue, Carsten; Masclee, Adrian A. M.; Keszthelyi, Daniel; Vork, Lisa; Tack, Jan; Talley, Nicholas J.; Simrén, Magnus; Aziz, Qasim; Ford, Alexander C.; Kruimel, Joanna W.; Conchillo, José M.
- Relation
- Neurogastroenterology & Motility Vol. 33, Issue 9, no. e14136
- Publisher Link
- http://dx.doi.org/10.1111/nmo.14136
- Publisher
- Wiley-Blackwell
- Resource Type
- journal article
- Date
- 2021
- Description
- Background: Due to important biases, conventional end-of-day and end-of-week assessment methods of gastrointestinal symptoms in functional dyspepsia (FD) are considered suboptimal. Real-time symptom assessment based on the experience sampling method (ESM) could be a more accurate measurement method. This study aimed to evaluate validity and reliability of an ESM-based patient-reported outcome measure (PROM) for symptom assessment in FD. Methods: Thirty-five patients with FD (25 female, mean age 44.7 years) completed the ESM-based PROM (a maximum of 10 random moments per day) and an end-of-day symptom diary for 7 consecutive days. On day 7, end-of-week questionnaires were completed including the Nepean Dyspepsia Index (NDI) and Patient Assessment of Gastrointestinal Symptom Severity Index (PAGI-SYM). Key Results: Experience sampling method and corresponding end-of-day scores for gastrointestinal symptoms were significantly associated (ICCs range 0.770–0.917). However, end-of-day scores were significantly higher (Δ0.329–1.031) than mean ESM scores (p < 0.05). Comparing ESM with NDI and PAGI-SYM scores, correlations were weaker (Pearson's r range 0.467–0.846). Cronbach's α coefficient was good for upper gastrointestinal symptoms (α = 0.842). First half-week and second half-week scores showed very good consistency (ICCs range 0.913–0.975). Conclusion and Inferences: Good validity and reliability of a novel ESM-based PROM for assessing gastrointestinal symptoms in FD patients was demonstrated. Moreover, this novel PROM allows to evaluate individual symptom patterns and can evaluate interactions between symptoms and environmental/contextual factors. ESM has the potential to increase patients' disease insight, provide tools for self-management, and improve shared decision making. Hence, this novel tool may aid in the transition toward personalized health care for FD patients.
- Subject
- experience sampling method; functional dyspepsia; patient-reported outcome measure; questionnaires; symptom perception
- Identifier
- http://hdl.handle.net/1959.13/1473458
- Identifier
- uon:49029
- Identifier
- ISSN:1350-1925
- Rights
- x
- Language
- eng
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